HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: HNRPF (P52597)
Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like protein mcs94-1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein F, N-terminally processed]
Gene: HNRNPF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	29924966, 31324722
Identification Methods	pull down, cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 415
+	Hs
		516343 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP1_HUMAN (1-410): 4.49e-80: 260: 13.66
+	Hs
		529208 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PAP1L_HUMAN (1-414): 2.82e-77: 252: 13.79
+	Hs
		529709 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP3_HUMAN (1-409): 1.76e-72: 240: 12.13
+	Hs
		528638 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HNRH1_HUMAN (1-413): 9.99e-69: 226: 74.82
+	Hs
		528841 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HNRH2_HUMAN (1-413): 9.35e-67: 220: 72.40
+	Hs
		529069 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP4_HUMAN (3-299): 6.9e-46: 169: 12.17
+	Hs
		528516 CFTR_HUMAN (1-1480): 0: 1031: 100.00		NUCL_HUMAN (75-370): 1.39e-11: 68.3: 19.21
+	Hs
		528637 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HNRH3_HUMAN (13-86): 4.01e-11: 66: 39.19
+	Sc
		376791 YCFI_YEAST (748-1433): 4.8e-56: 216: 14.59		PABP_YEAST (11-296): 1.71e-42: 158: 11.60
+	Hs
		582437 MRP9_HUMAN (129-648): 1.25e-56: 218: 14.61		NUCL_HUMAN (75-370): 1.39e-11: 68.3: 19.21