Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: AP2S1 (P53680)
AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (HA2 17 kDa subunit) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma2-adaptin)
Gene: AP2S1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 31324722
Identification Methods cross-linking study
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0030669 - clathrin-coated endocytic vesicle membrane
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1480
Hs

1 142
+ Hs
+ Hs

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Last updated: 15 Jul 2024