HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: HSP72 (P54652)
Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2) (Heat shock protein family A member 2)
Gene: HSPA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

The method score is based on:

Property	Details
Experiments	31324722, 17110338
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, cross-linking study
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane and 5 others more... GO:0009986 - cell surface GO:0016020 - membrane GO:0016887 - ATP hydrolysis activity GO:0019899 - enzyme binding GO:0051087 - protein-folding chaperone binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	1480
Hs

1	639

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024