HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: S10AA (P60903)
Protein S100-A10 (Calpactin I light chain) (Calpactin-1 light chain) (Cellular ligand of annexin II) (S100 calcium-binding protein A10) (p10 protein) (p11)
Gene: S100A10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	29924966
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0045921 - positive regulation of exocytosis
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 97
+	Hs
		529371 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HORN_HUMAN (1-97): 6.55e-32: 118: 30.69
+	Hs
		528643 CFTR_HUMAN (1-1480): 0: 1031: 100.00		S10AB_HUMAN (2-89): 4.9e-32: 109: 38.46
+	Hs
		529220 CFTR_HUMAN (1-1480): 0: 1031: 100.00		FILA2_HUMAN (3-97): 5.92e-28: 107: 34.34
+	Hs
		416344 CFTR_HUMAN (1-1480): 0: 1031: 100.00		S10A9_HUMAN (3-96): 8.76e-29: 101: 29.59
+	Hs
		396673 CFTR_HUMAN (1-1480): 0: 1031: 100.00		S10A8_HUMAN (1-93): 1.69e-23: 87.6: 25.00
+	Hs
		416559 CFTR_HUMAN (1-1480): 0: 1031: 100.00		S10A6_HUMAN (1-88): 2.47e-23: 86.9: 25.28
+	Hs
		528538 CFTR_HUMAN (1-1480): 0: 1031: 100.00		FILA_HUMAN (1-97): 2.57e-20: 85.7: 26.73
+	Hs
		528630 CFTR_HUMAN (1-1480): 0: 1031: 100.00		S10A7_HUMAN (3-96): 1.13e-20: 80.7: 21.88