HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: ACTZ (P61163)
Alpha-centractin (Centractin) (ARP1) (Actin-RPV) (Centrosome-associated actin homolog)
Gene: ACTR1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	26618866, 29924966, 31324722
Identification Methods	affinity chromatography technology, pull down, cross-linking study, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 376
+	Hs
		528863 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTB_HUMAN (7-376): 0: 580: 52.41
+	Hs
		528948 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTG_HUMAN (7-376): 0: 580: 52.67
+	Hs
		528913 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTA_HUMAN (5-376): 0: 576: 52.66
+	Hs
		528949 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTH_HUMAN (7-376): 0: 572: 52.94