HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	31324722, 29924966
Identification Methods	affinity chromatography technology, pull down, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 463
+	Hs
		528850 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PCBP3_HUMAN (2-114): 1.36e-12: 70.9: 16.24
+	Hs
		529153 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PCBP2_HUMAN (23-131): 1.39e-12: 70.9: 23.21
+	Hs
		529509 CFTR_HUMAN (1-1480): 0: 1031: 100.00		FUBP2_HUMAN (200-463): 3.03e-12: 70.9: 14.29
+	Hs
		529152 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PCBP1_HUMAN (23-127): 3.42e-12: 69.7: 23.15
+	Hs
		529983 CFTR_HUMAN (1-1480): 0: 1031: 100.00		IF2B2_HUMAN (267-463): 6.52e-12: 69.7: 15.00
+	Hs
		128010 CFTR_HUMAN (1-1480): 0: 1031: 100.00		IF2B3_HUMAN (272-463): 9e-09: 59.7: 14.57