HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31324722, 29924966
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 445
+	Hs
		529079 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB3_HUMAN (1-443): 0: 714: 93.23
+	Hs
		427992 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB5_HUMAN (1-429): 0: 711: 98.37
+	Hs
		529674 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB2B_HUMAN (1-430): 0: 710: 98.14
+	Hs
		529092 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB2A_HUMAN (1-430): 0: 707: 97.67
+	Hs
		529665 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB6_HUMAN (1-432): 0: 706: 92.36
+	Hs
		529204 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB8_HUMAN (1-427): 0: 704: 91.10
+	Hs
		1037335 MRP2_HUMAN (798-1466): 4.31e-56: 217: 15.74		TBB3_HUMAN (1-443): 0: 714: 93.23