HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: TRI32 (Q13049)
E3 ubiquitin-protein ligase TRIM32 (EC 2.3.2.27) (72 kDa Tat-interacting protein) (RING-type E3 ubiquitin transferase TRIM32) (Tripartite motif-containing protein 32) (Zinc finger protein HT2A)
Gene: TRIM32

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.608

Property	Details
Experiments	35156780, 26618866
Identification Methods	protein complementation assay, ubiquitin reconstruction, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 653
+	Hs
		528519 CFTR_HUMAN (1-1480): 0: 1031: 100.00		RO52_HUMAN (6-470): 1.76e-111: 345: 14.62
+	Hs
		528467 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TRI27_HUMAN (6-486): 2.41e-106: 333: 13.43
+	Hs
		529691 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TRIM5_HUMAN (6-470): 4.4e-92: 295: 13.09