HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	29924966, 31324722
Identification Methods	pull down, cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 471
+	Hs
		529069 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		516343 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		529709 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP3_HUMAN (66-459): 5.94e-61: 211: 13.88
+	Hs
		528557 CFTR_HUMAN (1-1480): 0: 1031: 100.00		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		529172 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		529541 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PABP5_HUMAN (78-205): 4.72e-26: 111: 26.76
+	Hs
		529208 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PAP1L_HUMAN (7-161): 7.22e-16: 82.3: 18.24
+	Hs
		529387 CFTR_HUMAN (1-1480): 0: 1031: 100.00		RAVR1_HUMAN (76-221): 8.34e-12: 69.4: 24.70
+	Sc
		376791 YCFI_YEAST (748-1433): 4.8e-56: 216: 14.59		PABP_YEAST (30-384): 3.77e-37: 145: 16.50