HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: PCBP1 (Q15365)
Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1) (Nucleic acid-binding protein SUB2.3)
Gene: PCBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31324722, 29924966
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 356
+	Hs
		529153 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44
+	Hs
		528886 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HNRPK_HUMAN (7-353): 1.94e-68: 223: 22.51
+	Hs
		128010 CFTR_HUMAN (1-1480): 0: 1031: 100.00		IF2B3_HUMAN (1-187): 4.45e-25: 107: 25.13
+	Hs
		529509 CFTR_HUMAN (1-1480): 0: 1031: 100.00		FUBP2_HUMAN (237-352): 3.22e-13: 72.5: 26.72
+	Hs
		528850 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PCBP3_HUMAN (1-85): 2.23e-11: 66.4: 28.74
+	Hs
		529983 CFTR_HUMAN (1-1480): 0: 1031: 100.00		IF2B2_HUMAN (237-350): 8.67e-09: 59: 17.39