HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: PCBP2 (Q15366)
Poly(rC)-binding protein 2 (Alpha-CP2) (Heterogeneous nuclear ribonucleoprotein E2) (hnRNP E2)
Gene: PCBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	26618866, 31324722, 29924966
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0019899 - enzyme binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 365
+	Hs
		528886 CFTR_HUMAN (1-1480): 0: 1031: 100.00		HNRPK_HUMAN (10-361): 2.75e-76: 244: 26.17
+	Hs
		529509 CFTR_HUMAN (1-1480): 0: 1031: 100.00		FUBP2_HUMAN (282-364): 1.14e-16: 83.3: 30.12
+	Hs
		529152 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PCBP1_HUMAN (93-173): 3.7e-12: 68.7: 28.40
+	Hs
		528850 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PCBP3_HUMAN (264-358): 5.07e-11: 65.2: 23.16