HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: DDX1 (Q92499)
ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB)
Gene: DDX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31324722, 29924966
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane and 1 others more... GO:0016887 - ATP hydrolysis activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 740
+	Hs
		133862 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DDX3X_HUMAN (1-380): 2.46e-40: 159: 13.47
+	Hs
		181679 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DDX3Y_HUMAN (1-380): 9.29e-40: 158: 13.97
+	Hs
		528498 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DDX5_HUMAN (1-381): 2.38e-34: 141: 11.96
+	Hs
		528696 CFTR_HUMAN (1-1480): 0: 1031: 100.00		IF4A3_HUMAN (3-72): 3.92e-11: 67.8: 30.00