HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: RRBP1 (Q9P2E9)
Ribosome-binding protein 1 (180 kDa ribosome receptor homolog) (RRp) (ES/130-related protein) (Ribosome receptor protein)
Gene: RRBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	31324722, 29924966
Identification Methods	affinity chromatography technology, pull down, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 1410
+	Hs
		522533 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH1_HUMAN (548-1215): 2.86e-23: 110: 13.02
+	Hs
		529767 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYO5C_HUMAN (619-1064): 1.48e-21: 104: 15.29
+	Hs
		529972 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH4_HUMAN (548-1208): 3.68e-21: 103: 13.91
+	Hs
		529354 CFTR_HUMAN (1-1480): 0: 1031: 100.00		KTN1_HUMAN (773-1408): 5.31e-21: 102: 12.92
+	Hs
		529587 CFTR_HUMAN (1-1480): 0: 1031: 100.00		COLA1_HUMAN (34-320): 5.75e-20: 98.9: 9.37
+	Hs
		528400 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH8_HUMAN (856-1399): 4.76e-19: 96.2: 16.52
+	Hs
		528357 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH6_HUMAN (559-1162): 5.36e-18: 92.7: 12.32
+	Hs
		528484 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DESP_HUMAN (681-1171): 5.53e-18: 92.7: 16.96
+	Hs
		522586 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH7_HUMAN (476-1148): 7.27e-18: 92.3: 12.67
+	Hs
		528675 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH9_HUMAN (490-1085): 2.8e-15: 83.9: 11.40
+	Hs
		528676 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH10_HUMAN (1009-1410): 1.11e-14: 81.9: 10.62
+	Hs
		528682 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH11_HUMAN (1007-1404): 2.08e-14: 81.2: 13.68
+	Hs
		441051 CFTR_HUMAN (1-1480): 0: 1031: 100.00		CO4A2_HUMAN (347-508): 6.72e-12: 72.7: 12.00
+	Hs
		529920 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TNR6B_HUMAN (73-635): 2.71e-10: 67.7: 13.40
+	Hs
		529340 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH14_HUMAN (1026-1394): 8.29e-09: 62.7: 16.71