HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: IPO11 (Q9UI26)
Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11)
Gene: IPO11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	17110338, 26618866
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 975
+	Hs
		528833 CFTR_HUMAN (1-1480): 0: 1031: 100.00		XPO2_HUMAN (1-974): 1.51e-166: 514: 15.32
+	Hs
		312172 CFTR_HUMAN (1-1480): 0: 1031: 100.00		IPO7_HUMAN (1-972): 3.4e-160: 500: 14.07
+	Hs
		178097 CFTR_HUMAN (1-1480): 0: 1031: 100.00		IPO8_HUMAN (1-970): 1.17e-153: 482: 14.30
+	Hs
		529511 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TNPO1_HUMAN (15-884): 1.46e-150: 470: 13.28
+	Hs
		162374 CFTR_HUMAN (1-1480): 0: 1031: 100.00		XPO1_HUMAN (10-972): 1.67e-116: 385: 10.00
+	Hs
		529589 CFTR_HUMAN (1-1480): 0: 1031: 100.00		IPO9_HUMAN (6-870): 3.9e-112: 372: 15.84
+	Dm
		1182055 Q7KTD0_DROME (788-1466): 6.87e-53: 206: 14.95		Q9VSD6_DROME (7-928): 2.08e-146: 464: 14.60
+	Dm
		1182040 Q7KTD0_DROME (788-1466): 6.87e-53: 206: 14.95		IPO9_DROME (4-870): 7.12e-127: 411: 19.28