HitPredict - High confidence protein-protein interactions

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.744

Method score

Annotation score

Interaction score

0.92

0.60

0.744

Property	Details
Experiments	15215316, 15611333, 19056735, 21898230, 11146634, 31596601, 19098309, 26618866
Identification Methods	enzymatic study, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property

Details

Experiments

15215316, 15611333, 19056735, 21898230, 11146634, 31596601, 19098309, 26618866

Identification Methods

enzymatic study, affinity chromatography technology, anti bait coimmunoprecipitation

Interaction Type

direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019899 - enzyme binding GO:0051087 - protein-folding chaperone binding
Homologous interactions	4

Property

Details

Interacting Pfam domains

Common GO terms

GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019899 - enzyme binding
GO:0051087 - protein-folding chaperone binding

Homologous interactions