HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: DJC16 (Q9Y2G8)
DnaJ homolog subfamily C member 16 (Endoplasmic reticulum DNA J domain-containing protein 8) (ER-resident protein ERdj8) (ERdj8)
Gene: DNAJC16

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26618866
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 782
+	Hs
		529648 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ERP44_HUMAN (135-504): 1.89e-50: 183: 12.70
+	Hs
		243278 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJA2_HUMAN (27-374): 2.08e-45: 170: 18.01
+	Hs
		529849 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DJB11_HUMAN (7-232): 6.1e-36: 141: 26.38
+	Hs
		279273 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJB5_HUMAN (26-138): 1.25e-35: 140: 33.07
+	Hs
		528576 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJB1_HUMAN (26-135): 5.33e-36: 140: 36.04
+	Hs
		528635 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJA1_HUMAN (26-213): 4.7e-35: 139: 26.98
+	Hs
		529482 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJB3_HUMAN (28-139): 1.68e-37: 139: 41.23
+	Hs
		529804 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DJB12_HUMAN (28-160): 6.64e-35: 138: 32.33
+	Hs
		529547 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DNJA3_HUMAN (29-106): 3.89e-19: 93.2: 54.43
+	Hs
		529425 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TXND5_HUMAN (151-250): 1.1e-14: 79.2: 25.24
+	Hs
		423122 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PDIA1_HUMAN (80-244): 3.2e-12: 71.9: 14.79
+	Hs
		528620 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PDIA3_HUMAN (103-251): 1.3e-11: 70: 13.07
+	Hs
		528451 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PDIA4_HUMAN (121-245): 6.82e-10: 64.6: 16.92
+	Sc
		633231 YCFI_YEAST (748-1433): 4.8e-56: 216: 14.59		MAS5_YEAST (26-244): 1.47e-35: 141: 24.43