HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: COPG1 (Q9Y678)
Coatomer subunit gamma-1 (Gamma-1-coat protein) (Gamma-1-COP)
Gene: COPG1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	26618866, 35156780, 29924966, 31324722
Identification Methods	affinity chromatography technology, protein complementation assay, pull down, cross-linking study, ubiquitin reconstruction, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 874
+	Hs
		529843 CFTR_HUMAN (1-1480): 0: 1031: 100.00		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Hs
		529041 CFTR_HUMAN (1-1480): 0: 1031: 100.00		AP1B1_HUMAN (14-872): 0: 650: 13.46
+	Hs
		528937 CFTR_HUMAN (1-1480): 0: 1031: 100.00		AP2B1_HUMAN (14-871): 0: 591: 12.40
+	Hs
		321478 CFTR_HUMAN (1-1480): 0: 1031: 100.00		AP2A1_HUMAN (24-874): 0: 582: 14.63