HitPredict

Interactor 1: CSPG2 (P13611)
Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M)
Gene: VCAN

Interactor 2: LYAM1 (P14151)
L-selectin (CD62 antigen-like family member L) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (Lymph node homing receptor) (TQ1) (gp90-MEL) (CD antigen CD62L)
Gene: SELL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 10950950, 10221651, 12556525
Identification Methods pull down, anti tag coimmunoprecipitation, solid phase assay
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF~EGF, EGF~Lectin_C, EGF~Sushi, Lectin_C~Lectin_C, Sushi~Sushi, EGF~V-set, Sushi~V-set
Common GO terms GO:0005509 - calcium ion binding
GO:0005615 - extracellular space
GO:0007155 - cell adhesion
GO:0030246 - carbohydrate binding
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 3396
Hs

1 372
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Last updated: 15 Jul 2024