HitPredict

Interactor 1: CSPG2 (P13611)
Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Glial hyaluronate-binding protein) (GHAP) (Large fibroblast proteoglycan) (PG-M)
Gene: VCAN

Interactor 2: CCL8 (P80075)
C-C motif chemokine 8 (HC14) (Monocyte chemoattractant protein 2) (Monocyte chemotactic protein 2) (MCP-2) (Small-inducible cytokine A8) [Cleaved into: MCP-2(6-76)]
Gene: CCL8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	11083865
Identification Methods	pull down, solid phase assay
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	IL8~V-set
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 3396 Hs			1 99
+	Hs
		486218 CSPG2_HUMAN (1-3396): 0: 1087: 100.00		CCL3_HUMAN (1-94): 4.53e-33: 111: 37.23
+	Hs
		528198 CSPG2_HUMAN (1-3396): 0: 1087: 100.00		CCL2_HUMAN (1-98): 9.7e-33: 111: 69.39
+	Hs
		528230 CSPG2_HUMAN (1-3396): 0: 1087: 100.00		CCL5_HUMAN (1-92): 1.3e-25: 92.7: 35.87
+	Hs
		134289 CSPG2_HUMAN (1-3396): 0: 1087: 100.00		CCL21_HUMAN (24-99): 2.47e-21: 83.1: 32.91
+	Hs
		530374 CSPG2_HUMAN (1-3396): 0: 1087: 100.00		CCL20_HUMAN (5-97): 3.28e-20: 79.2: 26.60
+	Hs
		486313 HPLN3_HUMAN (17-349): 7.56e-144: 455: 38.10		CCL3_HUMAN (1-94): 4.53e-33: 111: 37.23
+	Hs
		1055024 FAT1_HUMAN (3293-3390): 1.57e-14: 83.3: 10.00		CCL26_HUMAN (23-95): 4.79e-23: 86.6: 35.62
+	Hs
		815516 FAT4_HUMAN (3034-3196): 3.63e-10: 68.9: 13.86		XCL1_HUMAN (7-97): 1.01e-23: 88.9: 29.67
+	Hs
		943980 FAT4_HUMAN (3034-3196): 3.63e-10: 68.9: 13.86		X3CL1_HUMAN (8-95): 2.11e-21: 88.1: 34.07
+	Hs
		1167034 FAT4_HUMAN (3034-3196): 3.63e-10: 68.9: 13.86		CCL19_HUMAN (18-98): 1.65e-20: 80: 23.17