HitPredict

Interactor 1: RARG (P13631)
Retinoic acid receptor gamma (RAR-gamma) (Nuclear receptor subfamily 1 group B member 3)
Gene: RARG

Interactor 2: SMRD3 (Q6STE5)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C) (BRG1-associated factor 60C) (BAF60C)
Gene: SMARCD3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	17363140
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 483
+	Hs
		500368 RARB_HUMAN (1-453): 8.27e-140: 410: 72.03		SMRD3_HUMAN (1-483): 0: 685: 100.00
+	Mm
		509322 RARA_MOUSE (1-429): 1.64e-130: 386: 74.13		SMRD3_MOUSE (1-483): 0: 685: 99.79
+	Hs
		487986 RARA_HUMAN (1-426): 2.76e-129: 383: 74.41		SMRD3_HUMAN (1-483): 0: 685: 100.00
+	Hs
		587184 RXRA_HUMAN (4-422): 3.64e-127: 378: 30.00		SMRD3_HUMAN (1-483): 0: 685: 100.00
+	Hs
		369849 ESR1_HUMAN (2-448): 6.96e-112: 343: 22.02		SMRD3_HUMAN (1-483): 0: 685: 100.00
+	Hs
		782575 HNF4A_HUMAN (57-423): 2e-110: 336: 25.54		SMRD3_HUMAN (1-483): 0: 685: 100.00
+	Hs
		611457 NR4A1_HUMAN (1-419): 5.99e-105: 325: 32.94		SMRD3_HUMAN (1-483): 0: 685: 100.00
+	Hs
		510024 ERR1_HUMAN (28-419): 3.56e-101: 310: 27.16		SMRD3_HUMAN (1-483): 0: 685: 100.00
+	Hs
		370197 ESR1_HUMAN (2-448): 6.96e-112: 343: 22.02		SMRD1_HUMAN (27-483): 0: 606: 74.14
+	Hs
		782629 HNF4A_HUMAN (57-423): 2e-110: 336: 25.54		SMRD1_HUMAN (27-483): 0: 606: 74.14
+	Hs
		370147 ESR1_HUMAN (2-448): 6.96e-112: 343: 22.02		SMRD2_HUMAN (27-483): 0: 596: 70.36
+	Mm
		1142593 ERR2_MOUSE (4-418): 4.13e-109: 330: 27.66		SMRD1_MOUSE (27-483): 0: 604: 74.14
+	Hs
		782617 HNF4A_HUMAN (57-423): 2e-110: 336: 25.54		SMRD2_HUMAN (27-483): 0: 596: 70.36
+	Hs
		611490 NR4A1_HUMAN (1-419): 5.99e-105: 325: 32.94		SMRD1_HUMAN (27-483): 0: 606: 74.14
+	Hs
		1269351 ESR2_HUMAN (7-451): 2.68e-102: 316: 23.37		SMRD1_HUMAN (27-483): 0: 606: 74.14
+	Hs
		611483 NR4A1_HUMAN (1-419): 5.99e-105: 325: 32.94		SMRD2_HUMAN (27-483): 0: 596: 70.36
+	Hs
		1269285 ESR2_HUMAN (7-451): 2.68e-102: 316: 23.37		SMRD2_HUMAN (27-483): 0: 596: 70.36
+	Hs
		740544 PPARG_HUMAN (90-418): 2.61e-47: 171: 31.52		SMRD3_HUMAN (1-483): 0: 685: 100.00
+	Hs
		740582 PPARG_HUMAN (90-418): 2.61e-47: 171: 31.52		SMRD1_HUMAN (27-483): 0: 606: 74.14