HitPredict

Interactor 1: EF2 (P13639)
Elongation factor 2 (EF-2) (EC 3.6.5.-)
Gene: EEF2

Interactor 2: MK14 (Q16539)
Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)
Gene: MAPK14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	31980649, 23602568, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0034774 - secretory granule lumen and 1 others more... GO:1904813 - ficolin-1-rich granule lumen
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 858 Hs			1 360
+	Hs
		531033 EF2_HUMAN (1-858): 0: 1013: 100.00		CDK2_HUMAN (21-316): 3.8e-148: 421: 36.76
+	Rn
		398607 EF2_RAT (1-858): 0: 1015: 99.18		MK03_RAT (14-350): 2.59e-143: 412: 48.55
+	Hs
		173824 EF2_HUMAN (1-858): 0: 1013: 100.00		MK13_HUMAN (4-360): 1.04e-142: 410: 59.78
+	Sp
		145829 EF2_SCHPO (1-858): 0: 936: 64.34		HOG1_SCHPO (7-349): 1.58e-143: 411: 53.20
+	Hs
		625443 U5S1_HUMAN (4-856): 0: 815: 38.37		CDK2_HUMAN (21-316): 3.8e-148: 421: 36.76
+	Hs
		658947 U5S1_HUMAN (4-856): 0: 815: 38.37		MK01_HUMAN (10-350): 2.66e-138: 399: 47.70
+	Hs
		173903 EFGM_HUMAN (15-843): 0: 610: 21.65		MK13_HUMAN (4-360): 1.04e-142: 410: 59.78