HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: VGFR1 (P17948)
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)
Gene: FLT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 645 Hs			1 1338
+	Hs
		531749 PDIA4_HUMAN (1-645): 0: 571: 100.00		VGFR3_HUMAN (21-1330): 0: 755: 37.92
+	Hs
		671733 PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35		VGFR3_HUMAN (21-1330): 0: 755: 37.92
+	Hs
		531709 PDIA4_HUMAN (1-645): 0: 571: 100.00		PGFRA_HUMAN (11-666): 1.05e-59: 226: 19.41
+	Hs
		452339 PDIA4_HUMAN (1-645): 0: 571: 100.00		PGFRB_HUMAN (25-560): 1.37e-48: 191: 20.73
+	Hs
		507820 PDIA4_HUMAN (1-645): 0: 571: 100.00		FGFR1_HUMAN (129-520): 2.91e-36: 150: 12.14
+	Hs
		531720 PDIA4_HUMAN (1-645): 0: 571: 100.00		FGFR4_HUMAN (41-238): 1.53e-27: 122: 11.85
+	Hs
		426982 PDIA4_HUMAN (1-645): 0: 571: 100.00		CSF1R_HUMAN (29-324): 1.64e-21: 103: 15.14
+	Hs
		423164 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		VGFR2_HUMAN (2-438): 9.05e-45: 179: 12.15
+	Hs
		423118 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		FGFR1_HUMAN (129-520): 2.91e-36: 150: 12.14
+	Hs
		738235 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		FLT3_HUMAN (14-570): 5.07e-23: 108: 13.57
+	Hs
		607891 PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35		FGFR4_HUMAN (41-238): 1.53e-27: 122: 11.85