Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: PPIB (P23284)
Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP)
Gene: PPIB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.694

The method score is based on:

Property Details
Experiments 24981860, 30021884, 34079125, 22665516
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, pull down, isothermal titration calorimetry, nuclear magnetic resonance
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen
GO:0006457 - protein folding
GO:0042470 - melanosome
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 645
Hs

1 216
+ Rn
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Nc
+ Sc
+ Dm
+ Nc
+ Sc
+ Sc

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Last updated: 15 Jul 2024