HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: CALR (P27797)
Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP) (grp60)
Gene: CALR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 24981860, 34079125
Identification Methods affinity chromatography technology, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Calreticulin~Thioredoxin_6
Common GO terms GO:0003723 - RNA binding
GO:0005615 - extracellular space
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen
GO:0006457 - protein folding
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 645
Hs

1 417
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ At
+ Hs
+ Hs
+ Rn
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024