HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: ERP29 (P30040)
Endoplasmic reticulum resident protein 29 (ERp29) (Endoplasmic reticulum resident protein 28) (ERp28) (Endoplasmic reticulum resident protein 31) (ERp31)
Gene: ERP29

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0006457 - protein folding GO:0009306 - protein secretion GO:0009986 - cell surface and 1 others more... GO:0042470 - melanosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 645 Hs			1 261
+	Hs
		531739 PDIA4_HUMAN (1-645): 0: 571: 100.00		PDIA3_HUMAN (28-150): 5.13e-30: 119: 13.49
+	Hs
		531837 PDIA4_HUMAN (1-645): 0: 571: 100.00		PDIA6_HUMAN (13-251): 1.66e-29: 116: 17.48
+	Hs
		423123 PDIA4_HUMAN (1-645): 0: 571: 100.00		PDIA1_HUMAN (34-150): 7.83e-28: 112: 14.17
+	Rn
		751960 PDIA4_RAT (25-645): 0: 549: 87.12		PDIA4_RAT (24-154): 1.62e-27: 112: 15.56
+	Hs
		531910 PDIA4_HUMAN (1-645): 0: 571: 100.00		TXND5_HUMAN (57-255): 6.77e-20: 89.8: 15.27
+	Hs
		670616 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		ERP29_HUMAN (1-261): 6.75e-81: 245: 100.00
+	Hs
		671862 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		PDIA3_HUMAN (28-150): 5.13e-30: 119: 13.49
+	Hs
		1067759 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		PDIA6_HUMAN (13-251): 1.66e-29: 116: 17.48
+	Dm
		870429 PDI_DROME (53-504): 1.95e-49: 181: 20.13		Q3YMU0_DROME (28-150): 2.02e-25: 106: 13.49
+	Hs
		423286 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		PDIA1_HUMAN (34-150): 7.83e-28: 112: 14.17
+	Hs
		531897 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78
+	Ce
		1089129 PDI2_CAEEL (58-503): 8.42e-50: 182: 19.20		PDI1_CAEEL (38-160): 2.45e-24: 102: 17.46
+	Dm
		870452 PDI_DROME (53-504): 1.95e-49: 181: 20.13		PDIA6_DROME (15-137): 9.87e-24: 101: 15.08
+	Hs
		1220434 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		TXND5_HUMAN (57-255): 6.77e-20: 89.8: 15.27
+	Hs
		671819 PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51		PDIA3_HUMAN (28-150): 5.13e-30: 119: 13.49
+	Hs
		423107 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		PDIA1_HUMAN (34-150): 7.83e-28: 112: 14.17
+	Hs
		671722 PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35		PDIA3_HUMAN (28-150): 5.13e-30: 119: 13.49