HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: FKBP3 (Q00688)
Peptidyl-prolyl cis-trans isomerase FKBP3 (PPIase FKBP3) (EC 5.2.1.8) (25 kDa FK506-binding protein) (25 kDa FKBP) (FKBP-25) (FK506-binding protein 3) (FKBP-3) (Immunophilin FKBP25) (Rapamycin-selective 25 kDa immunophilin) (Rotamase)
Gene: FKBP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 645 Hs			1 224
+	Hs
		531724 PDIA4_HUMAN (1-645): 0: 571: 100.00		FKBP2_HUMAN (98-224): 2.6e-49: 159: 40.63
+	Dm
		817440 PDI_DROME (53-504): 1.95e-49: 181: 20.13		FKB12_DROME (109-224): 2.31e-48: 156: 41.38
+	Dm
		870460 PDI_DROME (53-504): 1.95e-49: 181: 20.13		Q9VGK3_DROME (107-224): 2.4e-44: 146: 41.18
+	Dm
		870450 PDI_DROME (53-504): 1.95e-49: 181: 20.13		Q9V3V2_DROME (111-223): 1.64e-42: 144: 39.13
+	Sc
		572722 PDI_YEAST (523-645): 2.02e-24: 109: 24.39		FKBP_YEAST (103-224): 6.97e-49: 157: 38.53
+	Sc
		572749 PDI_YEAST (523-645): 2.02e-24: 109: 24.39		FKBP2_YEAST (103-223): 9.12e-48: 155: 38.53
+	Nc
		223822 Q7S399_NEUCR (102-319): 7.58e-20: 95.3: 26.23		FKBP2_NEUCR (109-224): 6.64e-37: 130: 35.90
+	Nc
		223824 ERP38_NEUCR (544-635): 8.75e-13: 72.4: 43.30		FKBP2_NEUCR (109-224): 6.64e-37: 130: 35.90