HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: PLD3 (Q8IV08)
5'-3' exonuclease PLD3 (EC 3.1.16.1) (Choline phosphatase 3) (HindIII K4L homolog) (Hu-K4) (Phosphatidylcholine-hydrolyzing phospholipase D3) (Phospholipase D3) (PLD 3)
Gene: PLD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	35007762, 34349018
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 645 Hs			1 490
+	Hs
		531940 PDIA4_HUMAN (1-645): 0: 571: 100.00		PLD4_HUMAN (29-487): 0: 585: 42.68
+	Hs
		1217039 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		PLD3_HUMAN (1-490): 0: 772: 100.00
+	Hs
		423285 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		PLD3_HUMAN (1-490): 0: 772: 100.00
+	Hs
		1067758 PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51		PLD3_HUMAN (1-490): 0: 772: 100.00
+	Hs
		671860 PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35		PLD3_HUMAN (1-490): 0: 772: 100.00
+	Hs
		423322 PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11		PLD4_HUMAN (29-487): 0: 585: 42.68
+	Hs
		1067789 PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51		PLD4_HUMAN (29-487): 0: 585: 42.68
+	Hs
		671892 PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35		PLD4_HUMAN (29-487): 0: 585: 42.68