HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: DJC10 (Q8IXB1)
DnaJ homolog subfamily C member 10 (EC 1.8.4.-) (Endoplasmic reticulum DNA J domain-containing protein 5) (ER-resident protein ERdj5) (ERdj5) (Macrothioredoxin) (MTHr)
Gene: DNAJC10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 33957083, 34079125
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DnaJ~Thioredoxin, Thioredoxin~Thioredoxin, Thioredoxin~Thioredoxin_6
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen
GO:0015035 - protein-disulfide reductase activity
GO:0034976 - response to endoplasmic reticulum stress
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 645
Hs

1 793
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Last updated: 15 Jul 2024