HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: WWP1 (Q9H0M0)
NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 2.3.2.26) (Atrophin-1-interacting protein 5) (AIP5) (HECT-type E3 ubiquitin transferase WWP1) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1)
Gene: WWP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35264565
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 645 Hs			1 922
+	Hs
		531754 PDIA4_HUMAN (1-645): 0: 571: 100.00		NEDD4_HUMAN (84-919): 0: 723: 33.52
+	Hs
		671744 PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35		NEDD4_HUMAN (84-919): 0: 723: 33.52
+	Hs
		1067749 PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51		HUWE1_HUMAN (130-921): 1.4e-172: 559: 24.48
+	Sc
		572823 PDI_YEAST (523-645): 2.02e-24: 109: 24.39		TOM1_YEAST (439-921): 2.08e-156: 512: 31.81
+	Hs
		1220475 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		SMUF1_HUMAN (6-451): 5.28e-38: 154: 15.82
+	Hs
		1220473 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		SMUF2_HUMAN (7-381): 2.95e-31: 133: 16.24
+	Hs
		1067829 PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51		SMUF1_HUMAN (6-451): 5.28e-38: 154: 15.82
+	Sc
		572784 PDI_YEAST (523-645): 2.02e-24: 109: 24.39		RSP5_YEAST (16-424): 6.88e-44: 173: 20.05