HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: DJC16 (Q9Y2G8)
DnaJ homolog subfamily C member 16 (Endoplasmic reticulum DNA J domain-containing protein 8) (ER-resident protein ERdj8) (ERdj8)
Gene: DNAJC16

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~Thioredoxin, Thioredoxin~Thioredoxin, Thioredoxin~Thioredoxin_6
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 645 Hs			1 782
+	Hs
		531966 PDIA4_HUMAN (1-645): 0: 571: 100.00		ERP44_HUMAN (135-504): 1.89e-50: 183: 12.70
+	Hs
		532011 PDIA4_HUMAN (1-645): 0: 571: 100.00		DJB11_HUMAN (7-232): 6.1e-36: 141: 26.38
+	Hs
		532000 PDIA4_HUMAN (1-645): 0: 571: 100.00		DJB12_HUMAN (28-160): 6.64e-35: 138: 32.33
+	Hs
		532010 PDIA4_HUMAN (1-645): 0: 571: 100.00		DNJB9_HUMAN (9-152): 2.73e-36: 138: 34.72
+	Hs
		531910 PDIA4_HUMAN (1-645): 0: 571: 100.00		TXND5_HUMAN (151-250): 1.1e-14: 79.2: 25.24
+	Hs
		423123 PDIA4_HUMAN (1-645): 0: 571: 100.00		PDIA1_HUMAN (80-244): 3.2e-12: 71.9: 14.79
+	Hs
		531739 PDIA4_HUMAN (1-645): 0: 571: 100.00		PDIA3_HUMAN (103-251): 1.3e-11: 70: 13.07
+	Hs
		531897 PDIA4_HUMAN (1-645): 0: 571: 100.00		DJC10_HUMAN (56-248): 2.28e-11: 69.6: 12.00
+	Rn
		751960 PDIA4_RAT (25-645): 0: 549: 87.12		PDIA4_RAT (121-255): 6.2e-09: 61.5: 15.00
+	Mm
		1265749 PDIA6_MOUSE (392-645): 4.78e-51: 184: 19.85		ERP44_MOUSE (148-504): 5.73e-50: 182: 12.60
+	Mm
		1265101 TXND5_MOUSE (285-645): 3.7e-41: 156: 18.73		ERP44_MOUSE (148-504): 5.73e-50: 182: 12.60
+	Hs
		1220492 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		DJB11_HUMAN (7-232): 6.1e-36: 141: 26.38
+	Mm
		447645 PDIA1_MOUSE (4-197): 2.74e-32: 133: 25.76		ERP44_MOUSE (148-504): 5.73e-50: 182: 12.60
+	Rn
		1115513 DJC10_RAT (45-279): 6.21e-44: 170: 22.67		DJB11_RAT (7-232): 6.28e-36: 141: 26.38
+	Rn
		956846 DJC10_RAT (45-279): 6.21e-44: 170: 22.67		DNJB9_RAT (9-166): 1.67e-36: 138: 31.01
+	Hs
		1220434 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		TXND5_HUMAN (151-250): 1.1e-14: 79.2: 25.24
+	Rn
		1115511 DJC10_RAT (45-279): 6.21e-44: 170: 22.67		DJC10_RAT (72-354): 1.9e-14: 79.6: 14.33
+	Hs
		423286 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		PDIA1_HUMAN (80-244): 3.2e-12: 71.9: 14.79
+	Hs
		671862 DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47		PDIA3_HUMAN (103-251): 1.3e-11: 70: 13.07