HitPredict

Interactor 1: CEAM1 (P13688)
Carcinoembryonic antigen-related cell adhesion molecule 1 (Biliary glycoprotein 1) (BGP-1) (CD antigen CD66a)
Gene: CEACAM1

Interactor 2: CEAM8 (P31997)
Carcinoembryonic antigen-related cell adhesion molecule 8 (CD67 antigen) (Carcinoembryonic antigen CGM6) (Non-specific cross-reacting antigen NCA-95) (CD antigen CD66b)
Gene: CEACAM8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 11994468, 21982860
Identification Methods pull down, sandwich immunoassay, protein array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ig_2~ig, Ig_3~ig, V-set~ig, Ig_2~Ig_2, Ig_2~Ig_3, Ig_2~V-set, Ig_3~Ig_3, Ig_3~V-set, V-set~V-set
Common GO terms GO:0002682 - regulation of immune system process
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0009986 - cell surface
GO:0035579 - specific granule membrane
and 3 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 526
Hs

1 349
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+ Rn
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024