Interactor 1: TF (P13726)
Tissue factor (TF) (Coagulation factor III) (Thromboplastin) (CD antigen CD142)
Gene: F3

Interactor 2: PAR2 (P55085)
Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (G-protein coupled receptor 11) (Thrombin receptor-like 1) [Cleaved into: Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2]
Gene: F2RL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.55 0.458

The method score is based on:

Property Details
Experiments 16959886
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002020 - protease binding
GO:0005886 - plasma membrane
GO:0007596 - blood coagulation
GO:0030335 - positive regulation of cell migration
GO:0032757 - positive regulation of interleukin-8 production
and 1 others

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Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024