HitPredict

Interactor 1: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Interactor 2: FBN2 (P35556)
Fibrillin-2 [Cleaved into: Placensin]
Gene: FBN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 2912
+	Hs
		724401 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		FBN2_HUMAN (1-2912): 0: 1400: 100.00
+	Hs
		530367 CSPG2_HUMAN (4-221): 3.77e-46: 165: 17.00		FBN1_HUMAN (1742-2819): 1.44e-54: 214: 21.20
+	Hs
		533007 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LTBP4_HUMAN (5-896): 8.44e-35: 149: 16.19
+	Hs
		533105 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		NOTC3_HUMAN (8-486): 1.74e-24: 115: 14.18
+	Rn
		70327 G3V8R2_RAT (3-221): 2.12e-51: 180: 18.29		B2LYI9_RAT (16-278): 6.17e-24: 113: 18.35
+	Hs
		533081 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LTBP3_HUMAN (2-576): 3.9e-22: 107: 17.22
+	Hs
		957282 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		FBLN2_HUMAN (93-427): 2.59e-20: 101: 24.48
+	Hs
		1292818 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		JAG2_HUMAN (2-291): 1.2e-19: 99.3: 17.43
+	Hs
		533110 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		JAG2_HUMAN (2-291): 1.2e-19: 99.3: 17.43
+	Hs
		532909 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		NOTC1_HUMAN (2519-2834): 2.3e-19: 98.6: 14.12
+	Hs
		149947 NCAN_HUMAN (16-221): 1.24e-45: 163: 16.80		TENA_HUMAN (2-239): 3.7e-23: 111: 17.77
+	Hs
		530377 CSPG2_HUMAN (4-221): 3.77e-46: 165: 17.00		FBLN2_HUMAN (93-427): 2.59e-20: 101: 24.48
+	Hs
		532932 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		NOTC2_HUMAN (2615-2838): 8.38e-12: 73.9: 14.04
+	Hs
		980579 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		NOTC2_HUMAN (2615-2838): 8.38e-12: 73.9: 14.04
+	Hs
		417469 FCER2_HUMAN (5-220): 2.76e-51: 170: 20.08		NOTC2_HUMAN (2615-2838): 8.38e-12: 73.9: 14.04