HitPredict

Interactor 1: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Interactor 2: LAMB3 (Q13751)
Laminin subunit beta-3 (Epiligrin subunit bata) (Kalinin B1 chain) (Kalinin subunit beta) (Laminin B1k chain) (Laminin-5 subunit beta) (Nicein subunit beta)
Gene: LAMB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 1172
+	Hs
		1045112 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		LAMB3_HUMAN (1-1172): 0: 643: 100.00
+	Hs
		532932 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		NOTC2_HUMAN (255-723): 8.86e-43: 173: 15.05
+	Hs
		980579 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		NOTC2_HUMAN (255-723): 8.86e-43: 173: 15.05
+	Hs
		417469 FCER2_HUMAN (5-220): 2.76e-51: 170: 20.08		NOTC2_HUMAN (255-723): 8.86e-43: 173: 15.05
+	Hs
		533118 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LAMC3_HUMAN (430-664): 6.06e-20: 98.8: 19.28
+	Hs
		877442 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		LAMB2_HUMAN (449-748): 1.04e-15: 84.9: 14.54
+	Hs
		532920 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LAMB2_HUMAN (449-748): 1.04e-15: 84.9: 14.54
+	Hs
		172697 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		LAMA5_HUMAN (152-326): 1.32e-12: 74.9: 15.51
+	Hs
		172640 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LAMA5_HUMAN (152-326): 1.32e-12: 74.9: 15.51
+	Hs
		502807 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LAMC1_HUMAN (143-379): 5.36e-12: 72.6: 14.35
+	Hs
		532909 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		NOTC1_HUMAN (432-707): 5.63e-11: 69.5: 13.84
+	Hs
		433157 COL12_HUMAN (90-221): 3.82e-40: 147: 23.36		LAMB1_HUMAN (449-693): 3.08e-14: 80.3: 13.65