HitPredict

Interactor 1: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Interactor 2: HFE (Q30201)
Hereditary hemochromatosis protein (HLA-H)
Gene: HFE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C1-set~Lectin_C, Lectin_C~MHC_I
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 348
+	Hs
		382285 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		HLAA_HUMAN (7-346): 1.33e-140: 404: 36.42
+	Hs
		382559 CLC4E_HUMAN (92-221): 2.93e-35: 126: 14.60		HLAA_HUMAN (7-346): 1.33e-140: 404: 36.42
+	Hs
		532899 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		HLAF_HUMAN (7-346): 8.17e-119: 348: 35.26
+	Hs
		532886 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		HLAE_HUMAN (21-316): 4.13e-118: 347: 36.42
+	Hs
		533033 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		HMR1_HUMAN (9-345): 1.42e-107: 319: 36.10
+	Hs
		488269 CLC4G_HUMAN (38-221): 2.03e-39: 138: 18.62		HLAC_HUMAN (21-310): 5.15e-121: 355: 37.29
+	Hs
		354602 CLC4E_HUMAN (92-221): 2.93e-35: 126: 14.60		HLAB_HUMAN (7-347): 2.87e-124: 363: 36.02
+	Hs
		488420 CLC4E_HUMAN (92-221): 2.93e-35: 126: 14.60		HLAC_HUMAN (21-310): 5.15e-121: 355: 37.29
+	Hs
		674000 CLC4E_HUMAN (92-221): 2.93e-35: 126: 14.60		HLAF_HUMAN (7-346): 8.17e-119: 348: 35.26
+	Hs
		1278673 CLC4E_HUMAN (92-221): 2.93e-35: 126: 14.60		HMR1_HUMAN (9-345): 1.42e-107: 319: 36.10
+	Hs
		570381 MRC2_HUMAN (109-217): 3.74e-09: 58.3: 21.10		HLAG_HUMAN (7-336): 4.39e-127: 369: 35.42