HitPredict

Interactor 1: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Interactor 2: THSD4 (Q6ZMP0)
Thrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6)
Gene: THSD4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0062023 - collagen-containing extracellular matrix GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 1018
+	Hs
		1168366 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		THSD4_HUMAN (1-1018): 0: 705: 100.00
+	Hs
		314538 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ATS2_HUMAN (679-853): 8.98e-23: 107: 30.22
+	Hs
		533021 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ATS14_HUMAN (679-850): 2.3e-20: 99.6: 30.34
+	Hs
		1292817 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		ATS7_HUMAN (25-321): 6.98e-14: 78.8: 11.69
+	Hs
		533102 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ATS7_HUMAN (25-321): 6.98e-14: 78.8: 11.69
+	Hs
		533096 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ATS1_HUMAN (619-725): 8.83e-13: 75: 31.78
+	Hs
		1356546 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		ATS7_HUMAN (25-321): 6.98e-14: 78.8: 11.69