HitPredict

Interactor 1: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Interactor 2: ATS14 (Q8WXS8)
A disintegrin and metalloproteinase with thrombospondin motifs 14 (ADAM-TS 14) (ADAM-TS14) (ADAMTS-14) (EC 3.4.24.-)
Gene: ADAMTS14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 1223
+	Hs
		314538 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ATS2_HUMAN (37-1179): 0: 784: 52.32
+	Hs
		532946 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ADAM9_HUMAN (92-737): 1.74e-129: 418: 19.65
+	Hs
		532947 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ADA15_HUMAN (58-726): 2.82e-117: 387: 18.80
+	Hs
		533101 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ADA21_HUMAN (50-729): 4.86e-97: 328: 17.75
+	Hs
		1168366 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		THSD4_HUMAN (786-1104): 2.37e-34: 145: 20.78
+	Hs
		532990 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		THSD4_HUMAN (786-1104): 2.37e-34: 145: 20.78
+	Hs
		1292817 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		ATS7_HUMAN (729-1015): 2.81e-12: 73.8: 17.81
+	Hs
		533102 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ATS7_HUMAN (729-1015): 2.81e-12: 73.8: 17.81
+	Hs
		533096 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ATS1_HUMAN (972-1077): 8.38e-11: 68.8: 17.27
+	Hs
		1356546 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		ATS7_HUMAN (729-1015): 2.81e-12: 73.8: 17.81