HitPredict

Interactor 1: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Interactor 2: CHRD (Q9H2X0)
Chordin
Gene: CHRD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 955
+	Rn
		70327 G3V8R2_RAT (3-221): 2.12e-51: 180: 18.29		B2LYI9_RAT (558-954): 6.53e-57: 216: 13.15
+	Hs
		149947 NCAN_HUMAN (16-221): 1.24e-45: 163: 16.80		TENA_HUMAN (558-954): 8.86e-59: 222: 12.42
+	Hs
		532932 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		NOTC2_HUMAN (575-913): 9.96e-16: 84.5: 10.43
+	Hs
		980579 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		NOTC2_HUMAN (575-913): 9.96e-16: 84.5: 10.43
+	Hs
		434612 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		TSP1_HUMAN (597-947): 7.24e-13: 74.9: 9.59
+	Hs
		417469 FCER2_HUMAN (5-220): 2.76e-51: 170: 20.08		NOTC2_HUMAN (575-913): 9.96e-16: 84.5: 10.43
+	Hs
		533024 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		PXDN_HUMAN (708-766): 5.2e-11: 69.1: 33.90
+	Hs
		533118 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LAMC3_HUMAN (570-810): 1.02e-10: 67.9: 8.40
+	Hs
		877442 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		LAMB2_HUMAN (547-779): 2.93e-09: 63.3: 11.20
+	Hs
		532997 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		FRAS1_HUMAN (635-935): 2.18e-10: 67.2: 14.24
+	Hs
		172697 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		LAMA5_HUMAN (589-784): 4.99e-09: 62.9: 13.85
+	Hs
		502807 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LAMC1_HUMAN (563-792): 2.91e-10: 66.8: 10.13
+	Hs
		957282 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		FBLN2_HUMAN (738-911): 8.2e-09: 61.8: 22.03
+	Hs
		532920 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LAMB2_HUMAN (547-779): 2.93e-09: 63.3: 11.20
+	Hs
		172640 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		LAMA5_HUMAN (589-784): 4.99e-09: 62.9: 13.85
+	Hs
		1204969 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		FRAS1_HUMAN (635-935): 2.18e-10: 67.2: 14.24
+	Hs
		530377 CSPG2_HUMAN (4-221): 3.77e-46: 165: 17.00		FBLN2_HUMAN (738-911): 8.2e-09: 61.8: 22.03
+	Hs
		433157 COL12_HUMAN (90-221): 3.82e-40: 147: 23.36		LAMB1_HUMAN (558-807): 1.03e-10: 68.3: 9.15
+	Mm
		1147383 FREM1_MOUSE (31-221): 3.79e-35: 133: 17.95		FRAS1_MOUSE (635-945): 7.75e-09: 62.2: 14.32