HitPredict

Interactor 1: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Interactor 2: ATS1 (Q9UHI8)
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAM-TS 1) (ADAM-TS1) (ADAMTS-1) (EC 3.4.24.-) (METH-1)
Gene: ADAMTS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0008201 - heparin binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 967
+	Hs
		532946 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ADAM9_HUMAN (53-742): 1.44e-131: 418: 19.59
+	Hs
		532947 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ADA15_HUMAN (55-734): 4.66e-102: 340: 18.21
+	Hs
		1292817 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		ATS7_HUMAN (424-588): 9.35e-10: 64.9: 16.87
+	Hs
		1168366 PGCB_HUMAN (10-221): 9.83e-54: 186: 17.20		THSD4_HUMAN (858-955): 1.31e-09: 64.3: 37.50
+	Hs
		533102 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ATS7_HUMAN (424-588): 9.35e-10: 64.9: 16.87
+	Hs
		532990 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		THSD4_HUMAN (858-955): 1.31e-09: 64.3: 37.50
+	Hs
		314538 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ATS2_HUMAN (436-676): 1.54e-09: 64.1: 17.13
+	Hs
		533021 PRG2_HUMAN (1-222): 3.43e-57: 182: 100.00		ATS14_HUMAN (382-567): 1.55e-09: 64.1: 14.21
+	Hs
		1356546 PRG3_HUMAN (12-222): 3.37e-54: 174: 49.30		ATS7_HUMAN (424-588): 9.35e-10: 64.9: 16.87