HitPredict

Interactor 1: TNNT1 (P13805)
Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT)
Gene: TNNT1

Interactor 2: TNNT1 (P13805)
Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT)
Gene: TNNT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.815

The method score is based on:

Property	Details
Experiments	25416956, 16189514
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Troponin~Troponin
Common GO terms	GO:0003009 - skeletal muscle contraction GO:0005523 - tropomyosin binding GO:0005829 - cytosol GO:0005861 - troponin complex GO:0014883 - transition between fast and slow fiber and 4 others more... GO:0031014 - troponin T binding GO:0031444 - slow-twitch skeletal muscle fiber contraction GO:0045214 - sarcomere organization GO:0045932 - negative regulation of muscle contraction
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	278
Hs

1	278

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024