HitPredict

Interactor 1: GYS1 (P13807)
Glycogen [starch] synthase, muscle (EC 2.4.1.11) (Glycogen synthase 1)
Gene: GYS1

Interactor 2: PPR3C (Q9UQK1)
Protein phosphatase 1 regulatory subunit 3C (Protein phosphatase 1 regulatory subunit 5) (PP1 subunit R5) (Protein targeting to glycogen) (PTG)
Gene: PPP1R3C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	26186194, 28514442, 28330616, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005978 - glycogen biosynthetic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 737 Hs			1 317
+	Hs
		533700 GYS1_HUMAN (1-737): 0: 1422: 100.00		PPR3B_HUMAN (19-316): 3.55e-120: 348: 39.67
+	Hs
		873223 GYS2_HUMAN (1-658): 0: 1118: 72.53		PPR3C_HUMAN (1-317): 8.71e-163: 457: 100.00
+	Hs
		873222 GYS2_HUMAN (1-658): 0: 1118: 72.53		PPR3B_HUMAN (19-316): 3.55e-120: 348: 39.67
+	Sc
		648335 GYS2_YEAST (23-660): 0: 1061: 53.96		PIG1_YEAST (82-285): 2.64e-42: 156: 20.35
+	Sc
		615347 GYS1_YEAST (23-660): 0: 1066: 54.49		GAC1_YEAST (158-273): 1.96e-32: 129: 30.30
+	Sc
		615363 GYS1_YEAST (23-660): 0: 1066: 54.49		GIP2_YEAST (166-256): 5.55e-32: 126: 36.74
+	Sc
		615365 GYS1_YEAST (23-660): 0: 1066: 54.49		PIG2_YEAST (166-268): 4.48e-32: 126: 33.04
+	Sc
		648294 GYS2_YEAST (23-660): 0: 1061: 53.96		GAC1_YEAST (158-273): 1.96e-32: 129: 30.30
+	Sc
		648319 GYS2_YEAST (23-660): 0: 1061: 53.96		GIP2_YEAST (166-256): 5.55e-32: 126: 36.74
+	Sc
		648321 GYS2_YEAST (23-660): 0: 1061: 53.96		PIG2_YEAST (166-268): 4.48e-32: 126: 33.04