HitPredict

Interactor 1: RSR1 (P13856)
Ras-related protein RSR1 (EC 3.6.5.2)
Gene: RSR1

Interactor 2: CDC42 (P19073)
Cell division control protein 42 (EC 3.6.5.2) (Suppressor of RHO3 protein 2)
Gene: CDC42

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	30091649, 12960420, 14988726
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0000131 - incipient cellular bud site GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0005935 - cellular bud neck and 1 others more... GO:0071944 - cell periphery
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 272 Sc			1 191
+	Hs
		564467 RAP1B_HUMAN (1-168): 1.4e-87: 260: 60.12		RHOQ_HUMAN (4-179): 5.4e-85: 251: 66.48
+	Hs
		897878 RAP1B_HUMAN (1-168): 1.4e-87: 260: 60.12		RAC1_HUMAN (1-191): 4.15e-83: 245: 68.75
+	Hs
		893855 RAP1B_HUMAN (1-168): 1.4e-87: 260: 60.12		CDC42_HUMAN (1-191): 1.04e-80: 239: 80.11
+	Hs
		545300 RAP1B_HUMAN (1-168): 1.4e-87: 260: 60.12		RAC2_HUMAN (1-191): 1.83e-79: 236: 67.71
+	Hs
		897952 RAP1B_HUMAN (1-168): 1.4e-87: 260: 60.12		RHOJ_HUMAN (2-189): 4.76e-79: 236: 59.04
+	Hs
		897874 RAP1B_HUMAN (1-168): 1.4e-87: 260: 60.12		RHOA_HUMAN (5-191): 9.78e-79: 234: 51.34
+	Hs
		436236 RAP1B_HUMAN (1-168): 1.4e-87: 260: 60.12		RHOC_HUMAN (5-191): 5.48e-77: 230: 51.34
+	Hs
		564470 RAB1A_HUMAN (4-207): 5.56e-79: 239: 29.27		RHOQ_HUMAN (4-179): 5.4e-85: 251: 66.48
+	Hs
		892300 RAP1B_HUMAN (1-168): 1.4e-87: 260: 60.12		RAC3_HUMAN (1-177): 4.26e-77: 230: 71.19
+	Hs
		895028 RAB2A_HUMAN (4-188): 9.1e-80: 241: 32.80		RAC1_HUMAN (1-191): 4.15e-83: 245: 68.75
+	Hs
		895037 RAB2A_HUMAN (4-188): 9.1e-80: 241: 32.80		RHOG_HUMAN (1-191): 1.71e-81: 241: 58.64
+	Hs
		893849 RAB2A_HUMAN (4-188): 9.1e-80: 241: 32.80		CDC42_HUMAN (1-191): 1.04e-80: 239: 80.11
+	Hs
		545297 RAB2A_HUMAN (4-188): 9.1e-80: 241: 32.80		RAC2_HUMAN (1-191): 1.83e-79: 236: 67.71
+	Hs
		895271 RAB2A_HUMAN (4-188): 9.1e-80: 241: 32.80		RHOJ_HUMAN (2-189): 4.76e-79: 236: 59.04
+	Hs
		545307 RAB1A_HUMAN (4-207): 5.56e-79: 239: 29.27		RAC2_HUMAN (1-191): 1.83e-79: 236: 67.71
+	Hs
		895022 RAB2A_HUMAN (4-188): 9.1e-80: 241: 32.80		RHOA_HUMAN (5-191): 9.78e-79: 234: 51.34
+	Hs
		436232 RAB2A_HUMAN (4-188): 9.1e-80: 241: 32.80		RHOC_HUMAN (5-191): 5.48e-77: 230: 51.34
+	Hs
		892298 RAB2A_HUMAN (4-188): 9.1e-80: 241: 32.80		RAC3_HUMAN (1-177): 4.26e-77: 230: 71.19
+	Hs
		436244 RAB1A_HUMAN (4-207): 5.56e-79: 239: 29.27		RHOC_HUMAN (5-191): 5.48e-77: 230: 51.34
+	Ce
		1089984 RAP1_CAEEL (1-182): 3.59e-79: 239: 57.14		RHO1_CAEEL (5-191): 2.06e-74: 223: 53.48