Interactor 1: T2FB (P13984)
General transcription factor IIF subunit 2 (General transcription factor IIF 30 kDa subunit) (Transcription initiation factor IIF subunit beta) (TFIIF-beta) (Transcription initiation factor RAP30)
Gene: GTF2F2

Interactor 2: T2FA (P35269)
General transcription factor IIF subunit 1 (General transcription factor IIF 74 kDa subunit) (Transcription initiation factor IIF subunit alpha) (TFIIF-alpha) (Transcription initiation factor RAP74)
Gene: GTF2F1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 30415952, 24981860, 35235311, 37071682, 7827505, 7854423, 11183778, unassigned1913
Identification Methods pull down, affinity chromatography technology, cross-linking study, two hybrid, x-ray crystallography, split luciferase complementation, protein complementation assay, mammalian protein protein interaction trap, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains TFIIF_alpha~TFIIF_beta_N
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005674 - transcription factor TFIIF complex
GO:0006366 - transcription by RNA polymerase II
and 4 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 249
Hs

1 517
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024