HitPredict

Interactor 1: HAIR (P14003)
Protein hairy
Gene: hry

Interactor 2: HAIR (P14003)
Protein hairy
Gene: hry

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 14871887
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Hairy_orange~Hairy_orange, HLH~HLH
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000902 - cell morphogenesis
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001222 - transcription corepressor binding
and 18 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 337
Dm

1 337
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024