HitPredict

Interactor 1: ARAF (P14056)
Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1)
Gene: ARAF

Interactor 2: RASH (P20171)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: Hras

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	9679960
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1_1~Ras, RBD~Ras
Common GO terms	GO:0007265 - Ras protein signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 604 Rn			1 189
+	Mm
		384059 ARAF_MOUSE (1-604): 0: 582: 99.34		RASK_MOUSE (1-188): 1.68e-84: 249: 86.24
+	Hs
		348480 ARAF_HUMAN (1-604): 0: 568: 95.22		RASN_HUMAN (1-188): 6.47e-88: 257: 85.64
+	Hs
		348865 Q96II5_HUMAN (1-604): 0: 561: 94.09		RASN_HUMAN (1-188): 6.47e-88: 257: 85.64
+	Hs
		349820 ARAF_HUMAN (1-604): 0: 568: 95.22		RASK_HUMAN (1-188): 2.04e-84: 248: 86.24
+	Hs
		350452 Q96II5_HUMAN (1-604): 0: 561: 94.09		RASK_HUMAN (1-188): 2.04e-84: 248: 86.24
+	Mm
		384063 ARAF_MOUSE (1-604): 0: 582: 99.34		RASH_MOUSE (16-189): 5.68e-73: 219: 100.00
+	Hs
		488650 ARAF_HUMAN (1-604): 0: 568: 95.22		RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90
+	Hs
		349082 ARAF_HUMAN (1-604): 0: 568: 95.22		RASH_HUMAN (16-189): 5.68e-73: 219: 100.00
+	Hs
		348461 RAF1_HUMAN (12-604): 2.76e-179: 523: 59.77		RASN_HUMAN (1-188): 6.47e-88: 257: 85.64
+	Hs
		349785 RAF1_HUMAN (12-604): 2.76e-179: 523: 59.77		RASK_HUMAN (1-188): 2.04e-84: 248: 86.24
+	Rn
		442943 RAF1_RAT (12-604): 7.73e-179: 522: 59.27		RASK_RAT (1-188): 1.68e-84: 249: 86.24
+	Hs
		374007 RAF1_HUMAN (12-604): 2.76e-179: 523: 59.77		RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28
+	Hs
		488640 ARAF_HUMAN (1-604): 0: 568: 95.22		RRAS2_HUMAN (3-188): 6.39e-57: 179: 55.26
+	Hs
		374003 RAF1_HUMAN (12-604): 2.76e-179: 523: 59.77		RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90
+	Hs
		374854 RAF1_HUMAN (12-604): 2.76e-179: 523: 59.77		RAB1B_HUMAN (4-186): 2.6e-74: 223: 31.44
+	Hs
		349052 RAF1_HUMAN (12-604): 2.76e-179: 523: 59.77		RASH_HUMAN (16-189): 5.68e-73: 219: 100.00
+	Hs
		373983 RAF1_HUMAN (12-604): 2.76e-179: 523: 59.77		RAP1B_HUMAN (1-165): 2.18e-63: 195: 57.49
+	Hs
		374009 RAF1_HUMAN (12-604): 2.76e-179: 523: 59.77		RAP1A_HUMAN (1-165): 3.2e-62: 192: 56.89
+	Hs
		373597 RAF1_HUMAN (12-604): 2.76e-179: 523: 59.77		RALA_HUMAN (4-168): 3.3e-59: 185: 54.22
+	Hs
		373993 RAF1_HUMAN (12-604): 2.76e-179: 523: 59.77		RRAS2_HUMAN (3-188): 6.39e-57: 179: 55.26