Interactor 1: DHB1 (P14061)
17-beta-hydroxysteroid dehydrogenase type 1 (17-beta-HSD 1) (EC 1.1.1.51) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Estradiol 17-beta-dehydrogenase 1) (EC 1.1.1.62) (Placental 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 28C member 1)
Gene: HSD17B1

Interactor 2: DHB1 (P14061)
17-beta-hydroxysteroid dehydrogenase type 1 (17-beta-HSD 1) (EC 1.1.1.51) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Estradiol 17-beta-dehydrogenase 1) (EC 1.1.1.62) (Placental 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 28C member 1)
Gene: HSD17B1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 9525918
Identification Methods x-ray crystallography
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains adh_short~adh_short
Common GO terms GO:0003824 - catalytic activity
GO:0004303 - estradiol 17-beta-dehydrogenase [NAD(P)+] activity
GO:0005496 - steroid binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 20 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 328
Hs

1 328
+ Hs
+ Ss
+ At
+ At
+ At
+ At
+ At
+ Ec
+ At
+ At
+ At
+ At
+ At
+ At
+ Hs
+ Hs

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Last updated: 15 Jul 2024