HitPredict

Interactor 1: S10A6 (P14069)
Protein S100-A6 (5B10) (Calcyclin) (Prolactin receptor-associated protein) (S100 calcium-binding protein A6)
Gene: S100a6

Interactor 2: CYBP (Q9CXW3)
Calcyclin-binding protein (CacyBP) (Siah-interacting protein)
Gene: Cacybp

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.761

Property	Details
Experiments	12042313
Identification Methods	affinity chromatography technology, far western blotting, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	S_100~SGS
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0042803 - protein homodimerization activity GO:0044548 - S100 protein binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 89 Mm			1 229
+	Mm
		881596 S10A1_MOUSE (1-88): 6.6e-33: 111: 41.11		CYBP_MOUSE (1-229): 3.42e-98: 287: 100.00
+	Mm
		837567 S100B_MOUSE (3-89): 1.18e-28: 100: 38.20		CYBP_MOUSE (1-229): 3.42e-98: 287: 100.00
+	Hs
		639086 S100P_HUMAN (3-89): 3.05e-32: 109: 33.71		CYBP_HUMAN (6-229): 1.78e-93: 275: 93.33
+	Hs
		642995 S10A4_HUMAN (1-89): 5.94e-32: 108: 49.45		CYBP_HUMAN (6-229): 1.78e-93: 275: 93.33
+	Hs
		416703 S10A6_HUMAN (1-89): 3.66e-31: 106: 96.63		CYBP_HUMAN (6-229): 1.78e-93: 275: 93.33
+	Hs
		661446 S10A2_HUMAN (1-89): 6.84e-31: 106: 45.06		CYBP_HUMAN (6-229): 1.78e-93: 275: 93.33
+	Hs
		707353 S10A5_HUMAN (1-88): 1.72e-25: 92.2: 50.00		CYBP_HUMAN (6-229): 1.78e-93: 275: 93.33