HitPredict

Interactor 1: RL3 (P14126)
Large ribosomal subunit protein uL3 (60S ribosomal protein L3) (Maintenance of killer protein 8) (RP1) (Trichodermin resistance protein) (YL1)
Gene: RPL3

Interactor 2: SPB4 (P25808)
ATP-dependent rRNA helicase SPB4 (EC 3.6.4.13) (Suppressor of PAB1 protein 4)
Gene: SPB4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	16429126, 36929751, 37811893, 21825077
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000027 - ribosomal large subunit assembly GO:0003723 - RNA binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 387 Sc			1 606
+	Hs
		760346 RL3_HUMAN (1-386): 0: 656: 65.82		DDX18_HUMAN (6-467): 8.02e-159: 472: 29.61
+	Sc
		535102 RL3_YEAST (1-387): 0: 581: 100.00		HAS1_YEAST (6-467): 1.01e-156: 460: 30.98
+	Hs
		760184 RL3_HUMAN (1-386): 0: 656: 65.82		DDX55_HUMAN (6-594): 5.25e-122: 375: 34.05
+	Sc
		534888 RL3_YEAST (1-387): 0: 581: 100.00		DBP2_YEAST (2-402): 7.47e-126: 383: 25.43
+	Hs
		760033 RL3_HUMAN (1-386): 0: 656: 65.82		DDX10_HUMAN (21-472): 5.23e-47: 179: 29.67
+	Sc
		534880 RL3_YEAST (1-387): 0: 581: 100.00		DBP4_YEAST (21-467): 7e-51: 189: 31.36