HitPredict

Interactor 1: RL3 (P14126)
Large ribosomal subunit protein uL3 (60S ribosomal protein L3) (Maintenance of killer protein 8) (RP1) (Trichodermin resistance protein) (YL1)
Gene: RPL3

Interactor 2: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	16429126, 16287855, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000027 - ribosomal large subunit assembly GO:0003723 - RNA binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 387 Sc			1 291
+	Hs
		760191 RL3_HUMAN (1-386): 0: 656: 65.82		BRX1_HUMAN (26-286): 1.92e-85: 261: 47.91
+	Hs
		760321 RL3_HUMAN (1-386): 0: 656: 65.82		RPF2_HUMAN (1-285): 3.52e-77: 238: 17.57
+	Hs
		760327 RL3_HUMAN (1-386): 0: 656: 65.82		RPF1_HUMAN (7-251): 6.1e-62: 201: 17.13
+	Hs
		760337 RL3_HUMAN (1-386): 0: 656: 65.82		SSF1_HUMAN (12-281): 5.67e-45: 160: 12.87
+	Sc
		534952 RL3_YEAST (1-387): 0: 581: 100.00		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		534982 RL3_YEAST (1-387): 0: 581: 100.00		RPF1_YEAST (4-252): 5.84e-52: 173: 14.40
+	Sc
		534979 RL3_YEAST (1-387): 0: 581: 100.00		SSF1_YEAST (10-197): 9.05e-34: 129: 15.64