HitPredict

Interactor 1: GFAP (P14136)
Glial fibrillary acidic protein (GFAP)
Gene: GFAP

Interactor 2: UBP10 (Q14694)
Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10)
Gene: USP10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	28514442, 32814053
Identification Methods	affinity chromatography technology, two hybrid array, two hybrid pooling approach, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045111 - intermediate filament cytoskeleton
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 432 Hs			1 798
+	Hs
		777030 KRT85_HUMAN (6-384): 7.66e-89: 280: 32.20		UBP8_HUMAN (61-793): 7.74e-115: 376: 18.02
+	Hs
		1345488 KRT84_HUMAN (29-400): 3.57e-100: 312: 31.20		UBP36_HUMAN (369-795): 4.36e-90: 309: 22.94
+	Hs
		280779 KRT36_HUMAN (1-428): 9.2e-74: 240: 26.20		UBP8_HUMAN (61-793): 7.74e-115: 376: 18.02
+	Hs
		271020 NFL_HUMAN (45-378): 2.74e-76: 248: 48.21		UBP2_HUMAN (161-793): 7.79e-111: 352: 16.82
+	Hs
		271159 KRT35_HUMAN (2-377): 4.53e-74: 240: 28.50		UBP2_HUMAN (161-793): 7.79e-111: 352: 16.82